By Steven R. Goodman
This 3rd version of scientific telephone Biology makes a speciality of the clinical facets of cellphone biology vital to scientific scholars, dental scholars, veterinary scholars, and prehealth undergraduates. conserving a major specialize in eukaryotic mobile biology, the textual content explains basic mobile biology ideas within the context of organ structures and human and animal illness.
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This 3rd variation of clinical phone Biology specializes in the medical points of mobilephone biology very important to clinical scholars, dental scholars, veterinary scholars, and prehealth undergraduates. holding a main specialise in eukaryotic cellphone biology, the textual content explains basic mobilephone biology rules within the context of organ structures and human and animal disorder.
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Additional resources for Medical Cell Biology (3rd Edition)
For many years there were no established lines derived from normal human cells; the one established human cell line that was available was the HeLa cell line. These widely used cells were derived in the 1950s from the cervical cancer tissue of a woman named Henrietta Lacks. Normal animal cells must attach and spread out to grow (the “anchorage requirement” for growth); but HeLa cells, like some other established lines derived from cancer cells, have lost the anchorage requirement for growth, and can be grown in suspension like bacteria or yeast cells.
The hydrophobic effect drives structural rearrangement of lipids, including the formation of bilayers. Phospholipids placed in water would potentially disrupt the hydrogen bonding of water clusters. This causes the phospholipids to bury their nonpolar tails by forming micelles, bilayers, nonbilayer structures, or monolayers. The driving force of the hydrophobic effect is the tendency of water molecules to maximize their hydrogen bonding between the oxygen and hydrogen atoms. Which of the lipid structures is preferred depends on the lipids, as well as the environment.
A: From Goldberg MW, Allen TD. J Cell Biol 1992;119:1429, by permission of Rockefeller University Press; B: Modified from Alberts B, et al. Molecular Biology of the Cell, 4th ed. 1 μm A Cytosolic fibril Outer nuclear membrane Annular subunit CYTOSOL Nuclear evelope Lumenal subunit NUCLEUS Nuclear lamina 50 nM Column subunit Inner nuclear membrane Nuclear basket Ring subunit Nuclear fibril B often not easy to maintain the differentiated phenotype of these cells after prolonged growth in culture.
Medical Cell Biology (3rd Edition) by Steven R. Goodman