By Edited by Andrew D. Blann Edited by Gregory Y. H. Lip
Urban health center, Birmingham, united kingdom. Discusses the motives and outcomes of blood clots, how antithrombotic remedy works and its makes use of for sufferers. Addresses bleeding hazards, venous thromboembolism, atrial traumatic inflammation, peripheral vascular disorder, middle failure, and anticoagulation. ample halftone and colour illustrations. Softcover.
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Extra info for ABC of Antithrombotic
N Engl J Med 2002;345:1444-51 The flow diagram showing a classification of stroke by mechanism with estimates of the frequency of various categories of abnormalities is adapted from Albers GW et al, Chest 2001;119:300-20. Annual risk of stroke or vascular death among patients in various high risk subgroups is adapted from Wilterdink and Easton, Arch Neurol 1992;49:857-63. The figure showing thromboembolic and major haemorrhagic events in the IST is adapted from IST Collaborative Group. Lancet 1997;349:1569-81.
Primary patency rates of 80-90% can be expected at five to ten years. Thus, specific antithrombotic therapy is not indicated. However, once again, the presence of peripheral vascular disease needs antiplatelet therapy to reduce all cardiovascular end points. Percutaneous transluminal angioplasty Almost all patients undergoing percutaneous transluminal angioplasty have atherosclerotic peripheral vascular disease. As such, they should all be treated with aspirin or clopidogrel. Studies with radiolabelled platelets have found substantial platelet accumulation at the sites of angioplasty, and antiplatelet treatment reduces this.
The incidence of stroke is 1-2 cases in 1000 people a year in the Western world, and is probably slightly higher among African-Caribbeans than other ethnic groups. Cerebrovascular disorders are uncommon in people aged < 40 years, but there is a definite increase with age, with an incidence of 10 cases in 1000 people aged > 75 in a year. Stroke is slightly more common in men, but women tend to have a poorer prognosis because of a higher mean age at onset. The incidence of stroke has been declining in recent decades in many Western countries because of better population control of hypertension, smoking, and other risk factors.
ABC of Antithrombotic by Edited by Andrew D. Blann Edited by Gregory Y. H. Lip